| First Author | Mains PE | Year | 1986 |
| Journal | Immunogenetics | Volume | 23 |
| Issue | 6 | Pages | 357-63 |
| PubMed ID | 3013762 | Mgi Jnum | J:8324 |
| Mgi Id | MGI:56792 | Doi | 10.1007/BF00372667 |
| Citation | Mains PE (1986) A region flanking H-2K is duplicated to a distant site in most mouse t haplotypes. Immunogenetics 23(6):357-63 |
| abstractText | Mouse t haplotypes contain at least one inversion, which encompasses the major histocompatibility complex, relative to their wild-type counterparts. A DNA probe for a single copy sequence which flanks the H-2K region in inbred strains was found to have undergone further rearrangements in the t haplotypes. In most t haplotypes, this sequence is duplicated at a distant site, and the two regions show 1% recombination. The length of homology shared by the two sites is likely to be at least 10-15 kb. Three different alleles, as defined by restriction fragment length polymorphisms, were found for each of the two sites among different t haplotypes. These may reveal evolutionary relationships among these chromosomes. |
