First Author | Herrmann B | Year | 1986 |
Journal | Cell | Volume | 44 |
Issue | 3 | Pages | 469-76 |
PubMed ID | 3455895 | Mgi Jnum | J:8163 |
Mgi Id | MGI:56632 | Doi | 10.1016/0092-8674(86)90468-x |
Citation | Herrmann B, et al. (1986) Genetic analysis of the proximal portion of the mouse t complex: evidence for a second inversion within t haplotypes. Cell 44(3):469-76 |
abstractText | Genomic sequences derived from the mouse t complex by a microdissection cloning technique have been used as tools to obtain high resolution genetic maps of the wild-type and t haplotype forms of the most proximal portion of chromosome 17. Genetic mapping was performed through a recombinant inbred strain analysis and an analysis of partial t haplotypes. The accumulated data demonstrate the existence of a large inversion of genetic material, encompassing the loci of T and qk, within the proximal portion of t haplotypes. This newly described proximal inversion and the previously described distal inversion provide an explanation for the suppression of recombination observed along the length of t haplotype DNA in heterozygous mice. |