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Allele : Myo15a<sh2> myosin XVA; shaker 2

Primary Identifier  MGI:1857036 Allele Type  Radiation induced
Gene  Myo15a Inheritance Mode  Recessive
Strain of Origin  Mixed stock Is Recombinase  false
Is Wild Type  false
description  The Myo15sh2 mutation was discovered by Dobrovolskaia-Zavadskaia (J:15021) in descendants of an irradiated male.
molecularNote  The sequences of all 49 exons of this gene were analyzed. A G to A transition was found in codon 674 within exon 18 that produces a Cys to Tyr substitution that likely removes an actin binding site.
  • mutations:
  • Single point mutation
  • synonyms:
  • sh2,
  • sh2
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

Trail: Allele

0 Driven By

37 Publication categories

Trail: Allele