Primary Identifier | MGI:1857036 | Allele Type | Radiation induced |
Gene | Myo15a | Inheritance Mode | Recessive |
Strain of Origin | Mixed stock | Is Recombinase | false |
Is Wild Type | false |
description | The Myo15sh2 mutation was discovered by Dobrovolskaia-Zavadskaia (J:15021) in descendants of an irradiated male. |
molecularNote | The sequences of all 49 exons of this gene were analyzed. A G to A transition was found in codon 674 within exon 18 that produces a Cys to Tyr substitution that likely removes an actin binding site. |