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Publication : Spondyloarthropathy in progressive ankylosis (ank/ank) mice: morphological features.

First Author  Sampson HW Year  1988
Journal  Spine (Phila Pa 1976) Volume  13
Issue  6 Pages  645-9
PubMed ID  3175755 Mgi Jnum  J:109942
Mgi Id  MGI:3630118 Citation  Sampson HW (1988) Spondyloarthropathy in progressive ankylosis (ank/ank) mice: morphological features. Spine (Phila Pa 1976) 13(6):645-9
abstractText  Progressive ankylosis mice rapidly develop an ankylosing spondyloarthropathy that rapidly affects all of the articulations of the vertebral column. The disorder symmetrically affects the nonsynovial synchondroses and symphyses of the intervertebral spaces, the diarthrodial synovial apophyseal and costovertebral joints, and the sacroiliac joint. These joints present a clear progression from syndesmophyte formation through joint bridging to total fusion. The similarities and differences of the disorder identified in this mouse and human spondyloarthropathies are discussed.
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