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Publication : Anorexia, a recessive mutation causing starvation in preweanling mice.

First Author  Maltais LJ Year  1984
Journal  J Hered Volume  75
Issue  6 Pages  468-72
PubMed ID  6595305 Mgi Jnum  J:7689
Mgi Id  MGI:56158 Doi  10.1093/oxfordjournals.jhered.a109987
Citation  Maltais LJ, et al. (1984) Anorexia, a recessive mutation causing starvation in preweanling mice. J Hered 75(6):468-72
abstractText  A new autosomal recessive lethal mutation in mice, anorexia (anx), located close to pallid (pa) on chromosome (chr) 2, is described. Mutant mice are characterized by growth failure, an emaciated appearance, and abnormal behavior including headweaving, body tremors, uncoordinated gait, and hyperactivity during the late preweanling period. Data suggest that the mutant mice are not ingesting the levels of nutrients necessary to sustain life. This mutation may provide an important tool for studying the neurobiology of suckling behavior in the preweanling animal.
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