| Primary Identifier | MGI:1856658 | Allele Type | Spontaneous |
| Gene | Acd | Inheritance Mode | Recessive |
| Strain of Origin | DW/J | Is Recombinase | false |
| Is Wild Type | false |
| description | This mutation occurred in a subline of DW/J that lacks the Pou1f1dw mutation. J:18027 |
| molecularNote | This spontaneous mutation arose at The Jackson Laboratory in 1985. A point mutation (G to A) in the +5 position of the splice donor site in the third intron of the gene was revealed by DNA sequence analysis. RT-PCR analysis showed that aberrant transcripts were expressed from this allele, all of which are predicted to alter the reading frame of the protein. |
