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Publication : Animal model of systemic carnitine deficiency: analysis in C3H-H-2 degrees strain of mouse associated with juvenile visceral steatosis.

First Author  Kuwajima M Year  1991
Journal  Biochem Biophys Res Commun Volume  174
Issue  3 Pages  1090-4
PubMed ID  1996978 Mgi Jnum  J:31000
Mgi Id  MGI:78309 Doi  10.1016/0006-291x(91)91532-h
Citation  Kuwajima M, et al. (1991) Animal model of systemic carnitine deficiency: analysis in CC3H-H-2 degrees strain of mouse associated with juvenile visceral steatosis. Biochem Biophys Res Commun 174(3):1090-4
abstractText  We analyzed carnitine profiles in C3H-H-2 degrees strain of mouse associated with fatty liver, hyperammonemia and hypoglycemia (Koizumi et al., 1988). Carnitine levels in serum, liver and muscle of mouse with fatty liver were markedly decreased in comparison with those of control mouse (littermates without fatty liver). This is a useful animal model to analyze the role of carnitine in lipid, amino acid and carbohydrate metabolism.
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