First Author | Piletz JE | Year | 1978 |
Journal | Science | Volume | 199 |
Issue | 4325 | Pages | 181-3 |
PubMed ID | 619449 | Mgi Jnum | J:5911 |
Mgi Id | MGI:54388 | Doi | 10.1126/science.619449 |
Citation | Piletz JE, et al. (1978) Zinc deficiency in murine milk underlies expression of the lethal milk (lm) mutation. Science 199(4325):181-3 |
abstractText | The inability of nursing pups to survive on milk of mice homozygous for the recessive mutation, lethal milk (lm), is correlated with a reduction in zinc levels of both milk and pup carcass. Administration of zinc to pups nursing on lmlm dams reduces the observed mortality and morbidity. It is suggested that lm alters zinc transport from maternal blood to milk and that its study may provide useful information for understanding the rare human disease, acrodermatitis enteropathica. |