First Author | Lane PW | Year | 1976 |
Journal | J Hered | Volume | 67 |
Issue | 3 | Pages | 135-8 |
PubMed ID | 939913 | Mgi Jnum | J:5670 |
Mgi Id | MGI:54147 | Doi | 10.1093/oxfordjournals.jhered.a108687 |
Citation | Lane PW, et al. (1976) Myodystrophy, a new myopathy on chromosome 8 of the mouse. J Hered 67(3):135-8 |
abstractText | A new recessive mutation, myd, causing a diffuse and progressive myopathy in the mouse is described. Histopathological comparisons with normal littermates showed widely distributed focal lesions in all skeletal muscles of myd/myd. Body and organ weights of affected mice were considerably less than those of normal littermates and the mean lifespan of myodystrophic mice that survived weaning was 17 weeks with a range of 5 to 39 weeks. Myodystrophy is located on chromosome 8; it is linked to Os with about 6 percent and to Eso with about 37 percent recombination. |