| First Author | Traystman MD | Year | 1991 |
| Journal | Am J Pathol | Volume | 138 |
| Issue | 3 | Pages | 721-6 |
| PubMed ID | 1848043 | Mgi Jnum | J:11025 |
| Mgi Id | MGI:59467 | Citation | Traystman MD, et al. (1991) Susceptibility to Coxsackievirus B3-induced chronic myocarditis maps near the murine Tcr alpha and Myhc alpha loci on chromosome 14. Am J Pathol 138(3):721-6 |
| abstractText | This study was undertaken to determine the genetic control of host susceptibility to coxsackievirus B3 (CVB3)-induced chronic myocarditis in a mouse model. An autosomal recessive autoimmune myocardial disease (amd) gene (possibly more than one gene), which determined susceptibility to CVB3-induced chronic myocarditis in the A/J and DBA/2J inbred mouse strains, was mapped to a segment of chromosome 14. Data from both the AXB/BXA recombinant inbred (RI) strains and the B10.D2(57N) H-8b congenic mice supported this linkage relationship. Analysis of the AXB/BXA RI strain distribution patterns suggested that amd maps distal to the Np-2, Tcr alpha, and Myhc alpha loci. |
