First Author | Russell ES | Year | 1977 |
Journal | Mouse News Lett | Volume | 56 |
Pages | 40 | Mgi Jnum | J:31533 |
Mgi Id | MGI:79197 | Citation | Russell ES, et al. (1977) Cystic kidneys, ck. Mouse News Lett 56:40 |
abstractText | Full text of MNL contribution: 5. Cystic kidneys (ck). A new recessive mutation found in C57BL/6J-pa stock causes polycystic kidneys in homozygotes. The condition, always bilateral, becomes apparent at approximately 8 or 9 days of age, when the abdomen becomes enlarged, and becomes terminal at approximately 19 days of age. Penetrance is high. The excised kidneys measure approximately 1 cm X 2 cm at 16 days; cross-sections show them to be uniformly spongy throughout. This mutation is not linked to pa, nor is it sex-linked. (Russell and E.C. McFarland) |