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Publication : VIP-like immunoreactivity in the suprachiasmatic nuclei of a mutant anophthalmic mouse.

First Author  Laemle LK Year  1992
Journal  Brain Res Volume  589
Issue  1 Pages  124-8
PubMed ID  1422812 Mgi Jnum  J:2244
Mgi Id  MGI:50768 Doi  10.1016/0006-8993(92)91170-j
Citation  Laemle LK, et al. (1992) VIP-like immunoreactivity in the suprachiasmatic nuclei of a mutant anophthalmic mouse. Brain Res 589(1):124-8
abstractText  The suprachiasmatic nuclei (SCN) of mutant anophthalmic (strain ZRDCT-An) and sighted control mice was examined using light microscopic methods for cytoarchitecture and immunocytochemistry for vasoactive intestinal polypeptide (VIP). The SCN of the anophthalmic mice were asymmetrical, and quite variable in cytoarchitecture. Immunocytochemistry for VIP revealed strong staining of cells and fibers. Within the SCN, the distribution of VIP-immunoreactive cells was more diffuse in anophthalmic mice than in the controls; immunoreactive neurons were frequently observed in ectopic locations in the mutant animals.
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