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Publication : Testicular development in growth-retarded mice.

First Author  Kobayashi K Year  2007
Journal  Exp Anim Volume  56
Issue  5 Pages  393-7
PubMed ID  18075202 Mgi Jnum  J:137590
Mgi Id  MGI:3801263 Doi  10.1538/expanim.56.393
Citation  Kobayashi K, et al. (2007) Testicular development in growth-retarded mice. Exp Anim 56(5):393-7
abstractText  To assess delayed fertility in male growth-retarded (grt) mice with congenital primary hypothyroidism, their testes were chronologically examined. The testicular weight in grt mice was significantly lower than age-matched normal mice until 8 weeks but was comparable at 13 and 26 weeks. While normal mice had mature sperm cells in both testes and epididymides at 5 weeks, age-matched grt mice did not. The size of the seminiferous tubules in testes of grt mice was smaller than that of normal mice before 13 weeks but was comparable at 26 weeks. These findings suggest that male grt mice might need more than 13 weeks to develop mature testes.
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