| First Author | Montañez CS | Year | 1999 |
| Journal | Mol Genet Metab | Volume | 68 |
| Issue | 1 | Pages | 91-2 |
| PubMed ID | 10479487 | Mgi Jnum | J:59496 |
| Mgi Id | MGI:1351731 | Doi | 10.1006/mgme.1999.2887 |
| Citation | Montanez CS, et al. (1999) Linkage analysis of the hph-1 mutation and the GTP cyclohydrolase I structural gene. Mol Genet Metab 68(1):91-2 |
| abstractText | Our research establishes genetic linkage between the hph-1 mutation and the GTP-CH I structural gene. Our results indicate that these two loci are within an 8 cM region with 95% confidence. This finding lends additional support for the use of the hph-1 mouse mutant as a bona fide model system for the human disorder GTP-CH I to further our understanding of the molecular mechanisms involved in the disease pathology of GTP-CH I deficiency. Copyright 1999 Academic Press. |
