| First Author | Asakura A | Year | 2003 |
| Journal | Cancer Cell | Volume | 4 |
| Issue | 6 | Pages | 421-2 |
| PubMed ID | 14706332 | Mgi Jnum | J:88121 |
| Mgi Id | MGI:3029141 | Doi | 10.1016/s1535-6108(03)00313-1 |
| Citation | Asakura A, et al. (2003) Rhabdomyosarcomagenesis-Novel pathway found. Cancer Cell 4(6):421-2 |
| abstractText | Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children. Recent work presented in this issue of Cancer Cell by Fleischmann et al. on gene knockout mice revealed a remarkable molecular pathway for rhabdomyosarcomagenesis, in which Trp53/Fos double mutant mice developed RMS of the facial and orbital regions with high penetrance. This finding may provide novel molecular mechanisms for Rhabdomyosarcomagenesis and therapeutic implications for RMS patients. |
