First Author | Hollern DP | Year | 2014 |
Journal | Breast Cancer Res | Volume | 16 |
Issue | 3 | Pages | R59 |
PubMed ID | 25069779 | Mgi Jnum | J:210803 |
Mgi Id | MGI:5571917 | Doi | 10.1186/bcr3672 |
Citation | Hollern DP, et al. (2014) A genomic analysis of mouse models of breast cancer reveals molecular features of mouse models and relationships to human breast cancer. Breast Cancer Res 16:R59 |
abstractText | Genomic variability limits the efficacy of breast cancer therapy. To simplify the study of the molecular complexity of breast cancer, researchers have used mouse mammary tumor models. However, the degree to which mouse models model human breast cancer and are reflective of the human heterogeneity has yet to be demonstrated with gene expression studies on a large scale. |