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Allele : Mip<Cat-Lop> major intrinsic protein of lens fiber; cataract lens opacity

Primary Identifier  MGI:1857105 Allele Type  Spontaneous
Gene  Mip Inheritance Mode  Semidominant
Strain of Origin  STOCK Rb(6.15)1Ald Is Recombinase  false
Is Wild Type  false
molecularNote  A G-to-C transversion at position 151 of the encoded mRNA results in a non-conservative change at amino acid 51 from alanine to proline (p.A51P). This mutation inhibits targeting of the mutant product to the cell membrane.
  • mutations:
  • Single point mutation
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele