| First Author | Elhage R | Year | 2000 |
| Journal | Endocrinology | Volume | 141 |
| Issue | 1 | Pages | 462-5 |
| PubMed ID | 10614672 | Mgi Jnum | J:59156 |
| Mgi Id | MGI:1351095 | Doi | 10.1210/endo.141.1.7377 |
| Citation | Elhage R, et al. (2000) Loss of atheroprotective effect of estradiol in immunodeficient mice. Endocrinology 141(1):462-5 |
| abstractText | Estradiol significantly decreases fatty streak formation in the aortic root of chow-fed apolipoprotein E-deficient mice. In contrast, immunodeficient mice with homozygous disruption at the recombinase activating gene 2 loci present fatty streak development that is insensitive to estradiol. Lymphocytes thus appear to be required for development of the atheroprotective effect of estradiol in this mouse model. |
