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Allele : Cd247<tm1Lov> CD247 antigen; targeted mutation 1, Paul E Love

Primary Identifier  MGI:1857142 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cd247
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  Deletion of a genomic fragment containing exon 2 and an insertion of a neomycin gene into exon 4. Northern blot analysis demonstrated that small amounts of a mutant transcript could be detected in thymocyte and lymph node RNA derived from homozygous mice. Metabolic labeling and immunoprecipitation studies also confirmed that the protein was not detectable in thymocytes from homozygous mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • zeta/eta<->,
  • CD3zeta-KO,
  • CD3zeta-KO,
  • zeta -,
  • zeta-KO,
  • zeta-KO,
  • zeta/eta<->,
  • zeta -
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

32 Publication categories

Trail: Allele