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Publication : Generation of mutant mice lacking surface expression of CD4 or CD8 by gene targeting.

First Author  Mak TW Year  1992
Journal  J Autoimmun Volume  5 Suppl A
Pages  55-9 PubMed ID  1503636
Mgi Jnum  J:575 Mgi Id  MGI:49112
Doi  10.1016/0896-8411(92)90019-m Citation  Mak TW, et al. (1992) Generation of mutant mice lacking surface expression of CD4 or CD8 by gene targeting. J Autoimmun 5 Suppl A:55-9
abstractText  With the use of homologous recombination in embryonic stem cells, two new strains of mice lacking surface CD4 or CD8 expression have been generated. It is hoped that they will be useful mouse strains for the study of autoimmune diseases, tissue transplantation rejections and tumour rejections.
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