| First Author | Huber M | Year | 1998 |
| Journal | Infect Immun | Volume | 66 |
| Issue | 8 | Pages | 3968-70 |
| PubMed ID | 9673288 | Mgi Jnum | J:48826 |
| Mgi Id | MGI:1275859 | Doi | 10.1128/iai.66.8.3968-3970.1998 |
| Citation | Huber M, et al. (1998) Effective and long-lasting immunity against the parasite Leishmania major in CD8-deficient mice. Infect Immun 66(8):3968-70 |
| abstractText | The results of earlier investigations that tested whether CD8(+) T cells are required in the defense against Leishmania major have been inconsistent. We used CD8-deficient mice to directly address this issue. After primary infection with L. major, CD8-deficient mice controlled the infection for over 1 year and mounted strong T helper 1 cell responses. Thus, CD8(+) T cells are not required for the long-term control of a primary infection with L. major. |
