| First Author | Balkema GW | Year | 1983 |
| Journal | Science | Volume | 219 |
| Issue | 4588 | Pages | 1085-7 |
| PubMed ID | 6600521 | Mgi Jnum | J:6973 |
| Mgi Id | MGI:55444 | Doi | 10.1126/science.6600521 |
| Citation | Balkema GW, et al. (1983) Discrete visual defects in pearl mutant mice. Science 219(4588):1085-7 |
| abstractText | The mutant mouse pearl, characterized by its hypopigmentation, has a specific functional defect in a sensory system--the retina. The intact pearl mouse has reduced sensitivity in the dark-adapted condition. Normal sensitivity is restored by isolation and superfusion of the retina with bicarbonate-buffered Ringer solution, suggesting that the retinal expression of the pearl mutation depends on a diffusible substance. The pearl phenotype is described as a possible model for human congenital stationary night blindness. |
