Primary Identifier | MGI:1857008 | Allele Type | Radiation induced |
Gene | Dll3 | Inheritance Mode | Recessive |
Strain of Origin | (101/Rl x C3H/Rl)F1 | Is Recombinase | false |
Is Wild Type | false |
description | The pudgy mutation appeared in descendants of an X-rayed male at the Oak Ridge National Laboratory. (J:14975). It has been suggested that Dll3pu may be a recurrence of stub (sb), a skeletal mutant now extinct (J:245). |
molecularNote | Sequencing of Dll3 shows that Dll3pu mutants have a 4 bp deletion in the third exon leading to a frameshift and early truncation of the expected Dll3 product ahead of the conserved DSL domain. |