| First Author | Vivien L | Year | 2001 |
| Journal | Int Immunol | Volume | 13 |
| Issue | 6 | Pages | 763-8 |
| PubMed ID | 11369703 | Mgi Jnum | J:69776 |
| Mgi Id | MGI:2135427 | Doi | 10.1093/intimm/13.6.763 |
| Citation | Vivien L, et al. (2001) T lymphocytes need IL-7 but not IL-4 or IL-6 to survive in vivo. Int Immunol 13(6):763-8 |
| abstractText | The role of IL-4, -6 and -7 in the survival of T lymphocytes was studied in vivo. The decay of polyclonal populations of CD4(+) and CD8(+) T cells was monitored in thymectomized anti-cytokine receptor mAb-treated and/or cytokine-deficient mice. The lack of IL-4 or -6 did not have any detectable effect on T cell survival, but IL-7 played an important role in the survival of the naive T cell compartment, especially of naive CD4(+) T cells. |
