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Allele : Gt(ROSA)26Sor<tm1(tTA,tetO-Mir155)Fjsl> gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Frank J Slack
Primary Identifier  MGI:5431136 Allele Type  Targeted
Attribute String  Conditional ready, Inducible, Inserted expressed sequence, Transactivator Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  (C57BL/6J x SJL/J)F2
Is Recombinase  false Is Wild Type  false
molecularNote  A construct was inserted into the locus that contained the following elements (5' to 3'): the tetracycline transactivator (tTA), two poly-adenylation sequences, the tetracycline operator with minimal CMV promoter, a floxed neo cassette with 4 poly-adenylation sequences, the mouse transcript, and a poly-adenylation sequence. The locus promoter drives expression of tTA while the tet operator drives expression of the transcript only after cre mediated removal of the floxed neo-STOP cassette that can be repressed by doxycycline treatment.
  • mutations:
  • Insertion
  • synonyms:
  • Gt(ROSA)26Sor<tm1(tetO-Mir155)Fjsl>,
  • mir-155<LSLtTA>,
  • Gt(ROSA)26Sor<tm1(tetO-Mir155)Fjsl>,
  • mir-155<LSLtTA>
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

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0 Driven By

7 Publication categories

Trail: Allele




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