| First Author | Sanni LA | Year | 2004 |
| Journal | Infect Immun | Volume | 72 |
| Issue | 5 | Pages | 3054-8 |
| PubMed ID | 15102820 | Mgi Jnum | J:89479 |
| Mgi Id | MGI:3040532 | Doi | 10.1128/IAI.72.5.3054-3058.2004 |
| Citation | Sanni LA, et al. (2004) Cerebral edema and cerebral hemorrhages in interleukin-10-deficient mice infected with Plasmodium chabaudi. Infect Immun 72(5):3054-8 |
| abstractText | During a Plasmodium chabaudi infection in interleukin-10 (IL-10) knockout mice, there is greater parasite sequestration, more severe cerebral edema, and a high frequency of cerebral hemorrhage compared with infection of C57BL/6 mice. Anti-tumor necrosis factor alpha treatment ameliorated both cerebral edema and hemorrhages, suggesting that proinflammatory responses contributed to cerebral complications in infected IL-10(-/-) mice. |
