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Publication : Role of endogenous interleukin-12 in immune response to staphylococcal enterotoxin B in mice.

First Author  Lauw FN Year  2001
Journal  Infect Immun Volume  69
Issue  9 Pages  5949-52
PubMed ID  11500480 Mgi Jnum  J:71227
Mgi Id  MGI:2149319 Doi  10.1128/IAI.69.9.5949-5952.2001
Citation  Lauw FN, et al. (2001) Role of endogenous interleukin-12 in immune response to staphylococcal enterotoxin B in mice. Infect Immun 69(9):5949-52
abstractText  In the present study, the roles of interleukin 12 (IL-12) and IL-18 and their possible interaction during superantigen-induced responses were studied by injection of staphylococcal enterotoxin B (SEB) into mice. These data suggest that the role of IL-12 in SEB-induced responses is limited to sustaining gamma interferon release by an IL-18-independent mechanism.
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