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Allele : Tg(S100A8-cre,-EGFP)1Ilw transgene insertion 1, Irving L Weissman

Primary Identifier  MGI:4415239 Allele Type  Transgenic
Attribute String  Recombinase Gene  Tg(S100A8-cre,-EGFP)1Ilw
Strain of Origin  (C57BL/6 x C3H)F1 Is Recombinase  true
Is Wild Type  false
molecularNote  The human promoter drives expression of cre followed by an IRES sequence and EGFP in granulocytes and a fraction of myelomonocytic progenitors. Two founders were generated (no line information given). a A single copy of the transgene integrated at a single site on chromosome 5 (137,042,580-137,086,690; mouse mm10). This insertion leads to a 44 kb deletion of the host genome, resulting in complete deletion of the Serpine1 gene and partial deletion of the Ap1s1 gene.
  • mutations:
  • Insertion,
  • Intergenic deletion
  • synonyms:
  • Tg(S100A8-cre,-GFP)1Ilw,
  • Tg(S100A8-cre,-GFP)1Empa,
  • MRP8-Cre-ires/GFP,
  • Tg(S100A8-cre,-GFP)1Empa,
  • Mrp8cre<Tg>,
  • MRP8-Cre-ires/GFP,
  • Tg(S100A8-cre,-GFP)1Ilw,
  • Mrp8cre<Tg>
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1 Feature

Trail: Allele

Genome

0 Expresses

2 Mutation Involves

Trail: Allele

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

1 Driven By

Trail: Allele

100 Publication categories

Trail: Allele