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Allele : Jak3<tm1Ljb> Janus kinase 3; targeted mutation 1, Leslie J Berg

Primary Identifier  MGI:1857276 Allele Type  Targeted
Attribute String  Null/knockout Gene  Jak3
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette replaced a 0.6 kb fragment of the gene, which contains sequences encoding subdomains I to IV of the kinase domain. Protein immunoblots of lysates from bone marrow, spleen, and thymus showed no targeted protein.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Jak-3-,
  • Jak-3-,
  • Jak3<->,
  • Jak3<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

38 Publication categories

Trail: Allele