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Allele : Cyp7a1<tm1Rus> cytochrome P450, family 7, subfamily a, polypeptide 1; targeted mutation 1, David W Russell

Primary Identifier  MGI:1857285 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cyp7a1
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A genomic fragment containing part of exon 3, exon 4 and exon 5 was replaced with a neomycin selection cassette. Activity assays on extracts of liver microsomal memebrane preparations derived from homozygous mice demonstrated that no functional protein is made from this allele.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • CYP7A1-,
  • Cyp7-,
  • Cyp7-,
  • CYP7A1-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

20 Publication categories

Trail: Allele