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Allele : Plat<tm1Mlg> plasminogen activator, tissue; targeted mutation 1, Richard C Mulligan

Primary Identifier  MGI:1857288 Allele Type  Targeted
Attribute String  Null/knockout Gene  Plat
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  The gene was disrupted using neomycin resistance cassette. The vector replaced genomic sequences encoding most of the kringle-2 domain and part of the proteinase domain, including the catalytically essential histidine residue at position 326. Targeting was confirmed by the absence of gene specific mRNA and immunoreactivity.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • tPA<->,
  • t-PA<->,
  • tPA<->,
  • Plat<tm1>,
  • Plat<tm1>,
  • t-PA<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

5 Carried By

Trail: Allele

0 Driven By

157 Publication categories

Trail: Allele