| First Author | Eicher EM | Year | 1972 |
| Journal | Mouse News Lett | Volume | 47 |
| Pages | 36 | Mgi Jnum | J:13533 |
| Mgi Id | MGI:61720 | Citation | Eicher EM, et al. (1972) Hypophosphatemia (Hyp); Chr 7 linkage. Mouse News Lett 47:36 |
| abstractText | Full text of MNL contribution: New Mutants and Linkages: 1. Hypophosphatemia (Hyp). In MNL 41: 30, a dominant X-linked mutation causing shortening and thickening of the long bones, was described and was named osteopetrosis (Op). Further studies revealed that the defect was not osteopetrosis. We have found that mice carrying this mutation have a lower plasma phosphate level than their normal sibs. We have therefore renamed the mutation hypophosphatemia (Hyp) and we retract the symbol Op. A 3-point linkage cross of Female Bn Ta +/+ + Hyp x male + + +/Y is in progress. To date recombination between Hyp and Ta is 28.6%; between Hyp and Bn is 42.9%; between Ta and Bn is 14.3%. Thus the order is Bn - Ta - Hyp. It appears that Hyp is the most distally known gene on the X chromosome. (Eicher & Southard) |
