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Allele : Ptgs2<tm1Jed> prostaglandin-endoperoxide synthase 2; targeted mutation 1, Joe E Dinchuk

Primary Identifier  MGI:1857239 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ptgs2
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  A 1.8 kb genomic fragment containing exon 1 and the transcription and translation start sites was replaced with a neomycin selection cassette. Northern blot analysis on RNA derived from embryonic fibroblasts derived from homozygous embryos demonstrated that no detectable transcript was produced from this allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • COX-2-,
  • COX-2-,
  • Ptgs2-,
  • Ptgs2-,
  • COX2-,
  • Cox-2-,
  • Cox-2-,
  • COX2-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

97 Publication categories

Trail: Allele