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Allele : Emx1<tm1Jlr> empty spiracles homeobox 1; targeted mutation 1, John L R Rubenstein

Primary Identifier  MGI:1857433 Allele Type  Targeted
Attribute String  Null/knockout Gene  Emx1
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  Insertion of a PGK-neomycin resistance cassette replaced exon 1 and part of intron 1 of the Emx1 gene. Northern analysis of E14.5 embryos did not detect Emx1 transcript in homozygous mutant mice. The authors predict that the mutant allele would produce a truncated protein that lacks the N-terminus.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Emx1<null>,
  • Emx1<null>,
  • Emx-1-,
  • Emx-1-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

10 Publication categories

Trail: Allele