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Allele : Nf1<tm1Fcr> neurofibromin 1; targeted mutation 1, Fredrick Cancer Research and Development Center

Primary Identifier  MGI:1857444 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nf1
Transmission  Germline Strain of Origin  129S/SvEv-Gpi1<c>
Is Recombinase  false Is Wild Type  false
molecularNote  Insertion of a neomycin cassette in the opposite transcriptional orientation into exon 31 of the Nf1 gene. Exon 31 was chosen as the mutation site because several point mutations exist at this site in human NF1 patients. This allele is a null allele; no RNA or protein is made from this mutated allele.
  • mutations:
  • Insertion
  • synonyms:
  • Nf1<mut>,
  • Nf1<Fcr>,
  • Nf1-,
  • Nf1-,
  • Nf1<Fcr>,
  • Nf1<mut>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

7 Carried By

Trail: Allele

0 Driven By

94 Publication categories

Trail: Allele