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Allele : Ednra<tm1Ywa> endothelin receptor type A; targeted mutation 1, Masashi Yanagisawa

Primary Identifier  MGI:1857473 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ednra
Transmission  Germline Strain of Origin  129S7/SvEvBrd
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette replaced a genomic fragment containing exons 5 and 6, which encode the sixth and seventh transmembrane domains of the protein. Radioligand binding assays on samples derived from skin of homozygous embryos demonstrated that no functional protein was produced from this allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • ET/A -,
  • ET/A -
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

19 Publication categories

Trail: Allele