Primary Identifier | MGI:1857473 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ednra |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin selection cassette replaced a genomic fragment containing exons 5 and 6, which encode the sixth and seventh transmembrane domains of the protein. Radioligand binding assays on samples derived from skin of homozygous embryos demonstrated that no functional protein was produced from this allele. |