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Allele : Cyp2e1<tm1Gonz> cytochrome P450, family 2, subfamily e, polypeptide 1; targeted mutation 1, Frank J Gonzalez

Primary Identifier  MGI:1857483 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cyp2e1
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 2 was replaced with a neomycin resistance cassette. Northern blot analysis demonstrated that the normal transcript was not present in liver of homozygous mice. Western blot analysis confirmed the absence of the protein in liver extracts derived from homozygous mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Cyp2e1-,
  • Cyp2e1-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

57 Publication categories

Trail: Allele