Primary Identifier | MGI:1857340 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Rb1 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Insertion of a hygromycin resistance cassette into exon 19 disrupted the Rb1 gene. The authors predict that the Rb1 reading frame would be truncated upstream of the coding sequence for T-antigen binding domain number 2, and that therefore any gene product will be non functional. |