| Primary Identifier | MGI:1857384 | Allele Type | Transgenic |
| Gene | Grid2 | Strain of Origin | (C57BL/6 x CBA)F2 |
| Is Recombinase | false | Is Wild Type | false |
| description | Grid2ho-TgN37Inra, hotfoot transgenic, nonhomologous insert 37, Institut National de la Recherche Agronomique. As the result of insertion of a trangene into the hotfoot locus, a new allele was formed that causes a phenotype resembling hotfoot in homozygotes and in heterozygotes with the Grid2ho-4J allele (J:44452). A deletion in Grid2 mRNA in homozygotes for the new allele helps establish Grid2 as the site of the hotfoot mutations (J:48151). |
| molecularNote | Analysis of the transgene revealed that two complete and two truncated copies are inserted at the ho locus with an accompanying deletion of coding sequences. The resulting transcript contains a 4 kb deletion. |
