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Allele : Runx1<tm1Spe> runt related transcription factor 1; targeted mutation 1, Nancy A Speck

Primary Identifier  MGI:1857568 Allele Type  Targeted
Attribute String  Null/knockout Gene  Runx1
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 4, which encodes a portion of the DNA-binding domain, was replaced with a PGK-neo cassette. RT-PCR analysis showed a lack of normal transcript in homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Runx1<->,
  • Cbfa2<->,
  • Cbfa2<rd>,
  • Runx1<rd>,
  • Runx1<rd>,
  • Cbfa2<->,
  • Cbfa2<rd>,
  • Runx1<->,
  • Runx1<deltaE4>,
  • Runx1<deltaE4>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

28 Publication categories

Trail: Allele