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Allele : Ppara<tm1Gonz> peroxisome proliferator activated receptor alpha; targeted mutation 1, Frank J Gonzalez

Primary Identifier  MGI:1857774 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ppara
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette replaced 83 bp of the coding sequence in exon 8. Northern blot analysis did not detect a transcript of wild-type size on RNA derived from liver of homozygous mice. An larger abnormal transcript was detected. Western blot analysis did not detect PPARA protein in extracts derived from livers of homozygous mice.
  • mutations:
  • Insertion
  • synonyms:
  • mPPARalpha-,
  • PPARalpha-,
  • PPARalpha-,
  • PPARalpha-null,
  • Pparat<niJ>Gonz,
  • PPARalpha-null,
  • mPPARalpha-,
  • PPAR-alpha-,
  • Pparat<niJ>Gonz,
  • PPAR-alpha-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

6 Carried By

Trail: Allele

0 Driven By

406 Publication categories

Trail: Allele