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Allele : Chuk<tm1Aki> conserved helix-loop-helix ubiquitous kinase; targeted mutation 1, Shizuo Akira

Primary Identifier  MGI:1857735 Allele Type  Targeted
Attribute String  Null/knockout Gene  Chuk
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette replaced an exon encoding subdomain VI of the kinase catalytic domain. Northern and western blot analysis of embryonic fibroblast cells derived from homozygous mice confirmed that expression of the mRNA and protein was abolished.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • IKKalpha<->,
  • IKKalpha<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

16 Publication categories

Trail: Allele