Primary Identifier | MGI:1858117 | Allele Type | Chemically induced (ENU) |
Gene | Hbb | Strain of Origin | C57BL/6 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Analysis of the amino acid sequence of the variant beta-globin revealed that the valine at position 60 was changed to glutamic acid. The authors proposed that the mutational mechanism for such an alteration is an A-to-T transversion in codon 60. it is unclear whether the mutation was in the Hbb-b1 gene or the Hbb-b2 gene. |