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Allele : Morc1<Tg(Tyr)1Az> microrchidia 1; transgene insertion 1, Andrew R Zinn

Primary Identifier  MGI:1857787 Allele Type  Transgenic
Attribute String  Null/knockout, Reporter Gene  Morc1
Inheritance Mode  Recessive Strain of Origin  FVB/NHsd
Is Recombinase  false Is Wild Type  false
molecularNote  The random insertion of a transgene into the Morc gene also resulted in the deletion of a ~13 kb genomic fragment containing exons 2-4. The transgene contains a tyrosinase gene under the control of a polymerase (RNA) II (DNA directed) polypeptide A (Polr2a) promoter. RT-PCR analysis on RNA derived from testis of homozygous mice confirmed that no wild-type transcript was present; however an aberrant transcript containing transgene sequences fused to exon 5 and downstream sequences was expressed from this allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • microrchidia,
  • Tg(Tyr)1Az,
  • microrchidia,
  • Morc<TgN(Tyr)1Az>,
  • Morc<TgN(Tyr)1Az>,
  • Tg(Tyr)1Az,
  • morc,
  • morc
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

7 Publication categories

Trail: Allele