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Allele : Pik3cg<tm1Pngr> phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; targeted mutation 1, Josef M Penninger

Primary Identifier  MGI:1858013 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pik3cg
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  5 kb of this gene (amino acids 1-670) was replaced with a PGK-neo cassette via homologous recombination. Southern and Northern blot was used to confirm the null allele. Protein product was absent in neutrophils, T cells, and thymocytes from homozygous mutant animals as determined by Western blot.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • p110gamma-,
  • PI3Kgamma-,
  • PI3Kgamma-,
  • p110gamma-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

83 Publication categories

Trail: Allele