| Primary Identifier | MGI:1858040 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Fancc |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 8 and partial intronic flanking sequence was replaced by a neomycin cassette. RT-PCR analysis demonstrated that transcripts lacking exon 8 were produced from this allele as a result of splicing around the neo gene. However, this mutation event leads to frame shifted sequences downstream from exon 9. No protein product was detected in Western blots of liver extract from homozygous mice. |
