| Primary Identifier | MGI:1857982 | Allele Type | Targeted |
| Gene | Thbd | Transmission | Germline |
| Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The sequences encoding the wild-type protein were replaced with sequences that encoded a truncated form lacking the most carboxy-terminal 34 amino acid residues of the cytoplasmic domain, while retaining an in-frame stop codon. Immunohistochemistry and radioimmunoassay experiments confirmed that the mutant protein was expressed in a similar temporal and spatial manner to the normal protein. |
