| First Author | Dellovade TL | Year | 2000 |
| Journal | Nat Neurosci | Volume | 3 |
| Issue | 5 | Pages | 472-5 |
| PubMed ID | 10769387 | Mgi Jnum | J:61839 |
| Mgi Id | MGI:1355641 | Doi | 10.1038/74846 |
| Citation | Dellovade TL, et al. (2000) The two thyroid hormone receptor genes have opposite effects on estrogen-stimulated sex behaviors. Nat Neurosci 3(5):472-5 |
| abstractText | The two genes coding for thyroid hormone receptors (TR) alpha 1 and beta have opposite effects on female sex behaviors. Deletion of TRalpha 1 reduced them, whereas deletion of TRbeta actually increased them. These results could not be attributed to altered levels of hormones in the blood, general alterations in estrogen responsiveness or altered general activity. Instead, they indicate a previously unknown molecular mechanism upon which the two TR genes exert opposite influences. |
