Primary Identifier | MGI:1860610 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Adrb3 |
Transmission | Germline | Strain of Origin | FVB/N |
Is Recombinase | false | Is Wild Type | false |
description | This allele was generated by direct injection of DNA vectors into FVB/N zygotes. (J:30060) |
molecularNote | A 306bp genomic fragment containing the sequences encoding the third through the fifth transmembrane domains was replaced with a neomycin selection cassette. An RNase protection assay demonstrated that the encoded transcript was not detectable in brown adipose tissue of homozygous mice. |