| Primary Identifier | MGI:1860836 | Allele Type | Targeted |
| Attribute String | Modified regulatory region, Null/knockout | Gene | Rr128 |
| Inheritance Mode | Dominant | Transmission | Germline |
| Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
| Is Wild Type | false |
| description | This mutation results in a loss of silencing of the paternal allele in many endodermal and other tissues. |
| molecularNote | A loxP-flanked neomycin resistance cassette replaced the 1.2kb region of the promoter, corresponding to a cis-acting silencer element. This cassette was then excised in ES cells by cre-mediated recombination, resulting in the deletion of the silencer element. |
